의과대학 - 의과대학

  • 부교수 데이터사이언스
  • 이주상
    Lab 다음세대의학연구실

학술지 논문

  • (2024)  A systematic analysis of the landscape of synthetic lethality-driven precision oncology.  Med.  5,  1
  • (2023)  Increased interleukin-6/C-reactive protein levels are associated with the upregulation of the adenosine pathway and serve as potential markers of therapeutic resistance to immune checkpoint inhibitor-based therapies in non-small cell lung cancer.  JOURNAL FOR IMMUNOTHERAPY OF CANCER.  11,  10
  • (2023)  Prognostic implication of downregulated exosomal miRNAs in patients with sepsis: a cross-sectional study with bioinformatics analysis.  JOURNAL OF INTENSIVE CARE.  11,  1
  • (2023)  A landscape of response to drug combinations in non-small cell lung cancer.  NATURE COMMUNICATIONS.  14,  1
  • (2023)  Early infiltration of innate immune cells to the liver depletes HNF4a and promotes extra-hepatic carcinogenesis.  CANCER DISCOVERY.  22,  1
  • (2023)  Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma.  CELL REPORTS MEDICINE.  4,  2
  • (2022)  Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome.  MED.  4,  1
  • (2022)  CRBN is downregulated in lung cancer and negatively regulates TLR2, 4 and 7 stimulation in lung cancer cells.  CLINICAL AND TRANSLATIONAL MEDICINE.  12,  9
  • (2022)  USP15 negatively regulates lung cancer progression through the TRAF6-BECN1 signaling axis for autophagy induction.  CELL DEATH & DISEASE.  13,  4
  • (2022)  Deconvolving Clinically Relevant Cellular Immune Cross-talk from Bulk Gene Expression Using CODEFACS and LIRICS Stratifies Patients with Melanoma to Anti-PD-1 Therapy.  CANCER DISCOVERY.  12,  4
  • (2022)  AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer.  CANCER DISCOVERY.  12,  11
  • (2022)  USP8 regulates liver cancer progression via the inhibition of TRAF6-mediated signal for NF-κB activation and autophagy induction by TLR4.  Translational Oncology.  15,  1
  • (2021)  A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing.  NATURE COMMUNICATIONS.  12,  1
  • (2021)  Synthetic lethality-mediated precision oncology via the tumor transcriptome.  CELL.  184,  9
  • (2020)  Regulation of eIF2 alpha by RNF4 Promotes Melanoma Tumorigenesis and Therapy Resistance.  JOURNAL OF INVESTIGATIVE DERMATOLOGY.  140,  12
  • (2020)  Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors.  Nature Cancer.  1,  1
  • (2020)  p62 is Negatively Implicated in the TRAF6-BECN1 Signaling Axis for Autophagy Activation and Cancer Progression by Toll-Like Receptor 4 (TLR4).  CELLS.  9,  5
  • (2020)  Anti-tumor effects of anti-PD-1 antibody, pembrolizumab, in humanized NSG PDX mice xenografted with dedifferentiated liposarcoma.  CANCER LETTERS.  478,  1
  • (2020)  Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma.  NATURE COMMUNICATIONS.  11,  1
  • (2019)  Translational reprogramming marks adaptation to asparagine restriction in cancer.  NATURE CELL BIOLOGY.  15,  1